CRISPR Goes Global
CRISPR technology has revolutionized the field of gene editing, opening up new possibilities for scientific research, medical treatments, and agriculture. In this blog post, we will take a closer look at how CRISPR technology is being used across every continent on the globe. We will explore the innovative applications of CRISPR in each region and […]
Clinical CRISPR Success Demonstrates Need for Quality Control
The Clinical CRISPR Successes Are Stacking Up. But Where’s the Emphasis on Quality Control? In mid-September, Intellia released some promising data on two of their CRISPR-based therapeutics. These results are a significant milestone for genome editing and validation of its effectiveness in the clinic. However, the safety of CRISPR-based therapeutics has been a major concern […]
How the CRISPR Tomato and Genome Editing is Shaping the Future of Agriculture
How the CRISPR Tomato and Genome Editing is Shaping the Future of Agriculture One of the many applications of CRISPR-based genome editing is in agriculture, as it provides various benefits over conventional crop breeding strategies. Traditionally, crop developers have grappled with costly, laborious, time-consuming, and complicated selective breeding workflows to identify advantageous traits, such as […]
A Guide to CRISPR-Cas Mechanism of Action: Function and Optimization
The Missing Link in Pre-Clinical Genome Editing Workflows Currently, the “gold standard” genome editing workflows only produce one data type: in-cell editing events. With this single parameter, there is just one outcome to optimize around. Discovery programs typically focus on guide RNAs (gRNA) redesign or transfection conditions to maximize sensitivity and selectivity to troubleshoot CRISPR-Cas […]
Designing & Optimizing Better CRISPR Performance: Why CRISPR QC™ Exists
It’s been one decade and a Nobel Prize since Charpentier, Doudna, and colleagues first demonstrated the programmability of CRISPR-Cas systems.1 Since then, genome editing has exploded into nearly every field of biology. Today, news about editing technology in animals, plants, and humans occurs almost daily. Additional research has revealed a now-massive toolbox of CRISPR-Cas systems, […]
