RNP formation
Pre-screen gRNA efficiency, RNP assembly, and stability before costly sequencing and screening confirmation experiments.
- Identify the most effective gRNA
- Optimize multiplex gRNA & ratios
- Detect gRNA lot-to-lot variability
Insight Solutions
Transform gene editing workflows with real-time kinetic insights.
Maximize efficiency from discovery to commercialization with the CRISPR Analytics Platform™.
CRISPR Analytics Platform™
A failed CRISPR run leaves you with many questions. Quantitative kinetics help you answer them—before you spend weeks on downstream assays.
- Was the gRNA design suboptimal for efficient RNP formation?
- Did the Cas protein and gRNA combine properly to form the RNP complex?
- How strong was the binding affinity to the target DNA?
- What was the cleavage efficiency?
About CRISPR QC™
Confidently optimize key steps of your CRISPR workflow
Leverage insight solutions to gain accurate, reproducible data for confident decisions—from early discovery through manufacturing.
Empower discovery, development, and manufacturing with real-time quantitative insights into RNP formation, DNA target binding kinetics, cleavage activity, and more.
Discover moreInsight Solutions
Three kinetic pillars for your CRISPR program
Direct measurement of nucleic acid–protein interactions and cleavage—so you can troubleshoot faster and scale with confidence.
DNA target binding
Measure binding of target DNA amplicons to immobilized RNPs in real time to capture CRISPR-Cas DNA binding activity.
- Quantify binding of RNPs to amplicon
- Optimize designs or Cas proteins
- Understand environmental factors
Cleavage
Detect CRISPR-Cas cleavage activity in real time with high sensitivity on the CRISPR Analytics Platform™.
- Quantify cleavage efficiency
- Increase reproducibility
- Identify Cas activity variation
Why CRISPR QC
Accelerate gene editing decisions with measurable insight
Move faster by revealing what actually changes between doses, deliveries, reagents, and designs—before time and effort are lost.
Mechanism-aware measurement
Assays designed to surface functional behavior inside cells—not black-box endpoints that hide why outcomes change.
Time-resolved functional insight
Multi-parameter readouts that clarify how dose, delivery, and reagent performance drive editing outcomes over time.
0% Fewer blind optimization cycles
0–5 Actionable decisions per experiment
0–6× Faster identification of failure modes
0 Assay to compare doses, lots, and vendors
Your journey
Four simple steps from challenge to insight
- 1
Describe your workflow
Share targets, reagents, and what “good” looks like for your program.
- 2
Design the pilot
Our team proposes a focused assay plan aligned to your decision points.
- 3
Run & measure
Execute kinetic measurements on the CRISPR Analytics Platform™.
- 4
Deliver insight
Receive a clear report and recommended next steps to de-risk what comes next.
Testimonials
What teams value most
Featured use cases
Explore how researchers streamline gene editing workflows
Representative topics aligned to resources on crisprqc.com.
Optimizing RNP complexes and improving multiplex efficiency
Data-driven gRNA selection and complex optimization using quantitative kinetic readouts.
View resourcesAccelerating optimization with quantitative DNA binding analysis
Therapeutic development teams use binding kinetics to compare candidates with confidence.
View resourcesIn vitro cleavage assays that streamline workflows
High-sensitivity cleavage detection to quantify efficiency and variability.
Explore more use casesTechnology
Introducing the CRISPR-Chip™
Meet the graphene-based biosensor foundation behind quantitative in vitro analysis of CRISPR-Cas biochemistry.
Courtesy of UC Berkeley — learn how the chip enables kinetic measurements that support confident decisions.
CRISPR editing success starts with better measurements
Talk to our team about your research challenges and goals.