Knock out variability in your CRISPR-based development and manufacturing processes

Optimize CRISPR-Cas gene editing efficiency with Functional CRISPR QC Assays

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Integrate robust QC measures at critical points in your CRISPR workflow

Get the data you need to predict gene editing efficiency and optimize conditions for successful biologics production.

Read our case study to see how CDMOs and CROs can leverage functional CRISPR QC assays to:

  • Identify Cas9 enzymes with the highest cleavage activity
  • Pre-screen starting materials to select the right vendor
  • Verify Cas9 and gRNA lot-to-lot performance 
  • Predict editing efficiencies before conducting costly experiments or production runs

Confidently Optimize Key Steps Of Your CRISPR Workflow

Leverage our insight solutions to gain the accurate and reproducible data you need to make confident decisions and fast-track your breakthroughs.

RNP Formation

CRISPR QC™ Insight Solutions​

Direct measurement of nucleic acid-protein interactions enables you to pre-screen gRNA efficiency, RNP assembly, and RNP stability before costly sequencing and screening confirmation experiments.

  • Identify the most effective gRNA
  • Optimize multiplex gRNA
  • Optimize gRNA:Cas ratios
  • Determine optimal buffer conditions
  • Detect gRNA lot-to-lot variability
DNA Target Binding

CRISPR QC™ Insight Solutions

Directly measure the binding of target DNA amplicons to immobilized RNP complexes in real-time to capture CRISPR-Cas DNA binding activity.

  • Quantify binding of RNPs to amplicon
  • Optimize gRNA designs or Cas proteins
  • Make confident decisions to improve binding efficiency
  • Measure the influence of environmental factors on binding efficiency
CLEAVE

CRISPR QC™ Insight Solutions

Detect CRISPR-Cas cleavage activity in real-time with our highly-sensitive CRISPR Analytics Platform™.

  • Quantify target amplicon cleavage efficiency
  • Increase reproducibility of gene editing
  • Make confident data-driven decisions
  • Identify lot-to-lot variation in Cas activity

Ready to increase confidence in your bioprocessing workflows?

Download the Case Study